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Dyfed-Powys Police is at the scene of a serious collision on the A478 near Llandissilio in Pembrokeshire.
The incident was reported to police at 8.35am, and the ambulance and fire services also attended.
The collision involved a car and a bus carrying school children.
Sadly the driver of the car died at the scene. Next of kin have been advised and are being supported by specialist officers.
A number of children received minor injuries with two taken to hospital by ambulance with what are described as minor injuries.
The road is currently closed while investigations continue.
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